🧪 Coagulation Profile
Coagulation Profile is a group of blood tests that evaluate how well your blood clots. These tests help doctors identify bleeding disorders, clotting disorders, or monitor patients on blood-thinning medications.
🔹 Why is the Coagulation Profile Done?
To detect unexplained bleeding or bruising
To evaluate excessive clotting tendencies (thrombosis)
Before major surgery to assess bleeding risk
To monitor patients on anticoagulant therapy (e.g., warfarin, heparin)
To diagnose liver disease or vitamin K deficiency
🔹 Tests Included in Coagulation Profile
Prothrombin Time (PT):Â Measures the time it takes blood to clot.
INR (International Normalized Ratio):Â Standardized PT value, important for patients on blood thinners.
Activated Partial Thromboplastin Time (aPTT):Â Evaluates the intrinsic and common pathways of clotting.
Fibrinogen Assay:Â Determines fibrinogen levels, crucial for clot formation.
D-dimer Test:Â Detects abnormal clot breakdown, useful in ruling out thrombosis.
Factor VIII Assay:Â Identifies deficiency linked to Hemophilia A.
Factor IX Assay:Â Identifies deficiency linked to Hemophilia B.
Fibrin Degradation Products (FDP):Â Assesses excessive clot breakdown.
Antiphospholipid Antibodies (APLA):Â Detects antibodies linked to recurrent clotting or pregnancy loss.
Lupus Anticoagulant:Â Helps diagnose antiphospholipid syndrome.
Coomb’s Test: Detects antibodies against red blood cells.
Bleeding Time (BT):Â Assesses platelet function and primary hemostasis.
Clotting Time (CT): Basic test of blood clot formation.
🔹Why is it Done?
To investigate unexplained bleeding or bruising
To evaluate excessive clotting (thrombosis, DVT, PE)
Before surgery to assess bleeding risk
To monitor anticoagulant therapy (warfarin, heparin)
To diagnose hemophilia, liver disease, DIC, or vitamin K deficiency
🔹 Sample Required
Blood sample (venous)
🔹 Preparation
No fasting needed
Inform your doctor if you are on blood-thinning medications
Avoid intense physical activity before the test
