Polymerase Chain Reaction (PCR) Profile
Polymerase Chain Reaction (PCR) is an advanced molecular diagnostic technique used to detect genetic material (DNA or RNA) of infectious agents, viruses, and genetic markers. It is highly Sensitive, Specific, and Accurate, making it a gold standard for diagnosing infections, monitoring viral loads, and detecting genetic conditions.
🔹 Tests Included in PCR Profile
GeneXpert (CBNAAT): Rapid molecular test for detecting Tuberculosis (TB) and rifampicin resistance.
Hepatitis B Virus (HBV) DNA (Viral Load): Monitors HBV infection and guides treatment response.
HIV RNA PCR (Viral Load Test): Detects and quantifies HIV viral load for diagnosis and therapy monitoring.
HCV RNA PCR (Viral Load Test): Detects hepatitis C virus and tracks viral response to treatment.
HLA-B27 (Human Leukocyte Antigen B27): Genetic marker linked with autoimmune conditions like Ankylosing Spondylitis.
HPV (Human Papillomavirus) PCR: Detects high-risk HPV strains associated with Cervical and Other Cancers.
🔹 Why is it Done?
Early and accurate detection of viral infections
Monitoring viral load for HBV, HCV, and HIV patients
Diagnosing drug-resistant tuberculosis
Identifying autoimmune predispositions (HLA-B27)
Detecting cancer-associated viral infections (HPV)
🔹 Sample Required
Blood sample (for HBV, HCV, HIV, HLA-B27)
Sputum (for GeneXpert TB test)
Cervical/urogenital swab (for HPV)
